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CONTENTS
Section One
THE NORMAL LUNG
1 The Adult Lung: Structure and Function . . . . . . . . 3
Jacqueline J. Coalson
2 Development, Growth, and Aging of the Lung..............................15
Daphne deMello
Lynne M. Reid
Section Two
PATHOLOGIC DIAGNOSIS OF PULMONARY DISEASE
3 Cytologic Examination and Fine Needle Aspiration.........................27
Carlos W. M. Bedrossian
Rosa M. Davila
4 Biopsy Examination ........................41
Alberto M. Marchevsky
5 Study of Resected and Postmortem Lung Specimens ........................53
Mario J. Saldana
Section Three
PEDIATRIC LUNG PATHOLOGY AND METABOLIC DISORDERS OF THE LUNG
6 Congenital Malformations of the Larynx and Trachea..............................63
Benjamin H. Landing
7 Congenital Malformations of the Bronchi and Lung…………………71
Benjamin H. Landing
8 Emphysematous and Cystic Lesions ……………….. 79
Benjamin H. Landing
9 Genetic and Selected Nongenetic Disorders of the Respiratory Tract..........................85
Benjamin H. Landing
Benjamin H. Landing
11 Pulmonary Disease in the Pediatric Age Group………………..93
Miguel Reyes-Mugica
F. Gonzalez-Crussi
12 Pulmonary Involvement in Some Inborn Errors of Metabolism………………...105
Mamzumi Adachi
Section Four
PATHOLOGY OF ACUTE RESPIRATORY FAILURE
13 Cardiogenic Pulmonary Edema . . . . . . . . . . . . . . 117
Colin M. Blow
14 Noncardiogenic Pulmonary Edema and Diffuse Alveolar Damage……………….125
Joseph F. Tomashefski, Jr.
15 Iatrogenic Diffuse Alveolar Damage: Oxygen Toxicity and Radiation-Induced Injury . . . . . . . . 139
Joseph F. Tomashefski, Jr.
16 Drug-Induced Pulmonary Disease. . . . . . . . . . . . 149
Charles M. Lombard
17 Inhalation Injury to the Respiratory Tract . . . . . 159
Joanne L. Wright
Mario J. Saldana
18 Acute Pulmonary Thromboembolism and Other Forms of Pulmonary Embolization ........... 171
Colin M. Bloor
19 Acute Pulmonary Death and Forensic Pathology of the Lung………………179
Joseph H. Davis
Mario J. Saldana
Section Five
PATHOLOGY OF THE PULMONARY CIRCULATION
20 Pulmonary Hypertension Caused by Chronic Left Heart Failure, Obstruction of Pulmonary Venous Return, and Parenchymal Lung Disease . . . . . . . 203
Andrew Farb
Allen P. Burke
Renu Virmani
21Pulmonary Hypertension in Congenital Heart Disease…………………217
Ricardo Drut
22 Thromboembolic Pulmonary Hypertension, Intravenous Drug Addiction, and Rare Forms of
Pulmonary Embolization...................225
Andrew Farb
Allen P. Burke
Renu Virmani
Edwina J. Popek
23 Primary Pulmonary Hypertension and Venoocclusive Disease. . . . . . . . . . . . . . . . . . 235
Andrew Farb
Allen P. Burke
Renu Virmani
24 Pulmonary Hypertension and Pathology at High Altitudes……………….247
Mario J. Saldana
Javier Arias-Stella
25 Pathology of the Pulmonary Circulation Before and After Correction of Low Flow States………261
Ramiah Subramanian
Renu Virmani
Section Six
CHRONIC OBSTRUCTIVE PULMONARY DISEASE
Richard E. Sobonya
Daphne deMello
Lynne M. Reid
28 Bronchiectasis...........................295
Daphne deMello
Lynne M. Reid
29 Bronchia1 Asthma........................309
Philip C. Pratt
30 Small Airway Disease.....................317
Samuel A. Yousem
Section Seven
RESTRICTIVE OR INTERSTITIAL LUNG DISEASE
31 Usual or Nonspecific Interstitial Pneumonia, Interstitial Fibrosis, and the Honeycomb Lung…...325
Philip T. Cagle
32 Chronic Interstitial Pneumonias With Specific Histologic Features.......................341
Philip T. Cagle
33 Mixed Interstitial and Intraalveolar Processes . . . 357
Victor L. Roggli
Marcus S. Fisher, Jr.
34 The Pneumoconiosis: Coal Worker’s Pneumoconiosis……………369
Richard L. Naeye
35 The Pneumoconiosis: Silicosis and Silicatosis……..387
John J. Godleski
36 The Pneumoconiosis: Asbestosis…………..395
Victor L. Roggli
37 Rare Pneumoconiosis: Metalloconioscs . . . . . . . . 411
Victor L. Roggli
Section Eight
PULMONARY INFECTIONS
38 Usual Pneumonias Caused by Gram-Positive and Gram-Negative Bacteria . . . . . . . . . .. 425
Adolfo Firpo- Betancourt
Cesar A. Moran
39 Anaerobic and Unusual Bacterial Pneumonias…………….433
Aileen M. Marty
Ronald C. Neafie
Lloyd L. Smrkovski
40 Actinomycosis, Nocardiosis, and Botryomycosis……………….445
Aileen M. Marty
41Tuberculosis and Atypical Mycobactcrial Infections...............................451
Joseph F. Tomashefski, Jr.
42 Viral, Mycoplasmal, Rickettsial, and Chlamydial Infections...............................465
Anthony A. Gal
Steven M. Gordon
43 Fungal Diseses..........................477
Aileen M. Marty
Ronald C. Neafie
44 Protozoal and Helminthic Diseases . . . . . . . . . . . 489
Aileen M. Marty
Ronald C. Neafie
45 Pulmonary Pathology in Acquired Immunodeficiency Syndrome………….503
Peter Angritt
Joan M. Mones
Section Nine
TUMORS AND TUMORLIKE LESIONS OF THE LUNG AND PLEURA
46 Classification, Staging, and Etiology of Lung Cancer..........................523
Mario J. Saldana
Kasi S. Sridhar
Richard J. Thurer
47Adenocarcinoma.........................531
Mario J. Saldana
Joan M. Mones
Mario J. Saldana
Joan M. Mones
49 Small Cell Carcinoma.....................555
Michael James Gaffey
Stacey E. Mills
50 Large Cell Carcinoma..................... 571
Bruce Mackay
51 Carcinoid and Other Neuroendocrine Tumors .……… 581
William D. Travis
52 Bronchial Gland Tumors…................ 597
Alberto M. Marchevsky
53 Papillary Tumors of Surface Epithelium . . . . . . . 609
Mario J. Saldana
Joan M. Mones
54 Mixed Epithelial-Mesenchymal Tumors . . . . . . . . 617
Michael N. Koss
Cesar A. Moran
J. Thomas Stocker
55 Lymphomas and Other Lymphoproliferative Lesions . . . . . . . . . . . . . 631
Gordon N. Gephardt
Raymond R. Tubbs
56 Mesenchymal Tumors……………… 645
Cesar A. Moran
57 Malignant Mesothelioma and Other Pleural Tumors..........................657
Carlos W. M. Bedrossian
58 Miscellaneous Tumors.....................673
Nicholas J. Hruby
Michael James Gaffey
Stacey E. Mills
59 Metastatic Lung Cancer....................691
Saul Suster
60 Pulmonary Metastases of Extrapulmonary Tumors……….701
Saul Suster
61Tumorlike Lesions of the Lung and Pleura . . . . . 711
Osamu Matsubara
Eugene J. Mark
Section Ten
IMMUNOLOGIC LUNG DISEASE
62 Goodpasture Syndrome and the Diffuse Alveolar Hemorrhage Syndrome....................723
Stephen M. Bonsib
63 Allergic Bronchopulmonary Aspergillosis, Mucoid Impaction of Bronchi, and Bronchocentric Granulomatosis..........................733
Michael N. Koss
William D. Travis
64 Eosinophilic Pneumonia……………….745
Charles M. Lombard
65 Hypersensitivity Pneumonitis . . . . . . . . . . . . . . . 755
Roberto Barrios
Yale Rosen
67Pulmonary Involvement in Collagen-Vascular Disorders........................781
J. T. Lie
Charles M. Lombard
Michael N. Koss
William D. Travis
70 Pulmonary Involvement in Systemic Vasculitides.............................811
J. T. Lie
71Transplantation Pathology... . . . . . . . . . . . . . . . 819
Samuel A. Yousem
Section Eleven
MISCELLANEOUS TOPICS
72 Pathology of the Upper Airways............. 829
Louis H. Weiland
73 Pathology of the Trachea and Main Bronchi ………..843
Mario J. Saldana
74 Pathology of the Mediastinum. . . . . . . . . . . . . . . 853
Saul Suster
Cesar A. Moran
75 Pathology of the Pleura....................863
Stephen M. Bonsib
J. Carlos Manivel
76 Pathology of the Chest Wall and Diaphragm ….…….. 875
J. Carlos Manivel
77 Environmental and Occupational Aspects of Pulmonary Disease.....................883
John. E. Craighead
Index..................................889
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